ATP binding to a multisubunit enzyme: statistical thermodynamics analysis

Due to inter-subunit communication, multisubunit enzymes usually hydrolyze ATP in a concerted fashion. However, so far the principle of this process remains poorly understood. In this study, from the viewpoint of statistical thermodynamics, a simple model is presented. In this model, we assume that the binding of ATP will change the potential of the corresponding enzyme subunit, and the degree of this change depends on the state of its adjacent subunits. The probability of enzyme in a given state satisfies the Boltzmann's distribution. Although it looks much simple, this model can fit the recent experimental data of chaperonin TRiC/CCT well. From this model, the dominant state of TRiC/CCT can be obtained. This study provided a new way to understand biophysical processes by statistical thermodynamics analysis

Texas Business Review, March 1975

The Business Situation in Texas; Growth of the Texas Economy, 1959-1974; Texas Construction; The Energy Economy: U.S. Oil Imports and Exports, 1860-1974Bureau of Business Researc

Student residences: Time for a partnership approach?

Acknowledgements The authors would like to thank the large number of participants in this research for their contribution. Among others these include university secretaries and estate directors, QMPF, Real Capital Analytics, Barclays, Bank of Ireland, Unite, Student Roost, GSA, Sanctuary Housing and Campus Life.Peer reviewedPostprin

Sport sponsorship alliances: relationship management for shared value

© 2014, © Emerald Group Publishing Limited. Purpose – Using a case study of an international sport event, the purpose of this paper is to examine the inter-organisational relationship between a sport event property and its corporate sponsors. Design/methodology/approach – Interviews were conducted with personnel from the national sport organisation responsible for the delivery of this major event, and from four of its corporate sponsorship partners. Findings – The findings indicated that both formal and informal governance were critical to the relationships underpinning these sponsorship alliances. From a dyadic perspective, it was found that the satisfaction of sponsorship partners had two key elements: tangible commercial benefits from the sponsor-sponsee alliance, and the less tangible but nonetheless valuable relationship support within the partnership. In short, partner satisfaction and alliance stability stemmed from relational constructs and the balance of formal governance mechanisms. Originality/value – This paper explores the variables that generate value and maintain alliance stability for improved sponsorship governance. These findings, while focused on a single case study, have implications for research in the field of sponsorship and to the area of business-to-business relationships more broadly

Paradoxical popups: Why are they hard to catch?

Even professional baseball players occasionally find it difficult to gracefully approach seemingly routine pop-ups. This paper describes a set of towering pop-ups with trajectories that exhibit cusps and loops near the apex. For a normal fly ball, the horizontal velocity is continuously decreasing due to drag caused by air resistance. But for pop-ups, the Magnus force (the force due to the ball spinning in a moving airflow) is larger than the drag force. In these cases the horizontal velocity decreases in the beginning, like a normal fly ball, but after the apex, the Magnus force accelerates the horizontal motion. We refer to this class of pop-ups as paradoxical because they appear to misinform the typically robust optical control strategies used by fielders and lead to systematic vacillation in running paths, especially when a trajectory terminates near the fielder. In short, some of the dancing around when infielders pursue pop-ups can be well explained as a combination of bizarre trajectories and misguidance by the normally reliable optical control strategy, rather than apparent fielder error. Former major league infielders confirm that our model agrees with their experiences.Comment: 28 pages, 10 figures, sumitted to American Journal of Physic